Vol. 31 No. 4 (2025) | Digital Journal of Ophthalmology

Still image from video clip of positive Seidel test

Original Articles
A simple mathematical approach to identifying baseline predictors of the effectiveness of carbonic anhydrase inhibitors in intraocular pressure reduction
From normalcy to pandemic: analyzing cataract surgery patterns through case volumes and Google Trends (2014-2020)

Case Reports
A unique cause of blepharoptosis associated with RYR1 mutation
Unilateral choroidal involvement revealing an acute leukemia
Subconjunctival triamcinolone acetonide injection around lumen of XEN Gel Stent effectively resolves persistent choroidal effusion
Effective response to intravitreal faricimab in a patient with myopic neovascular membrane resistant to aflibercept
Management of large submacular hemorrhage in a patient undergoing neurosurgical intervention for moyamoya

Grand Rounds
A 46-year-old woman with bilateral white retinal vessels
A 43-year-old woman with nontraumatic profuse ocular hemorrhage

Images & Videos
Vitreous cyst in a 73-year-old man
Digitally assisted phaco-DMEK surgery
Seidel-positive corneal laceration
Massive submacular hemorrhage in pseudoxanthoma elasticum
Straatsma syndrome: unilateral myelinated retinal nerve fibre layer, high myopia, and amblyopia
Spontaneous resolution of conjunctival hemorrhagic lymphangiectasia

Published: 2025-12-31

$Relationships between a percentage IOP reduction achieved by a CAI and ξ at different baseline trabecular outflow facility and uveoscleral outflow fraction.$

A simple mathematical approach to identifying baseline predictors of the effectiveness of carbonic anhydrase inhibitors in intraocular pressure reduction

Wichapol Dendumrongsup, MD

PDF

Monthly interest in the search term "cataract."

From normalcy to pandemic: analyzing cataract surgery patterns through case volumes and Google trends (2014-2020)

Vinit Majmudar, BS, Monali S. Ardeshna, BS, Raghav Vadhul, MD

PDF

Preoperative photograph of patient showing bilateral ptosis.

A unique cause of blepharoptosis associated with RYR1 mutation

Imanouel M. Samai, MD, Brian R. Wong, MD

PDF

Bone marrow smear showing invasion of large granular blasts.

Unilateral choroidal involvement revealing an acute leukemia

Soundouss Sebbata, MD, Taoufik Abdellaoui, PhD, Soufiane Laksir, MD, Soukaina Laaouina, MD, Houda Brarou, MD, Yassine Mouzari, PhD

PDF

Subconjunctival injection of triamcinolone acetonide (40 mg/mL) around the XEN stent resolved the choroidal detachment in 1 week.

Subconjunctival triamcinolone acetonide injection around lumen of XEN Gel Stent effectively resolves persistent choroidal effusion

Anny M. S. Cheng, MD, Geetha G. Vedula, MD, Shailesh K. Gupta, MD, MBA, Argyrios Agritis, BS, David T. Y. Yang, BS, Elizabeth S. Yang, BS, Aarup A. Kubal, MD

PDF

OCT of the right eye showing no intraretinal fluid but persistence of hyperreflective material after a single dose of intravitreal faricimab.

Effective response to intravitreal faricimab in a patient with myopic neovascular membrane resistant to aflibercept

Nelson C. Capelanes, MD, Bernardo K. Moscovici, MD, Caio V. Regatieri, MD, PhD, Renata F. B. Sugai, MD, Ana A. C. Concer, MD

PDF

Appearance of “puff of smoke” concerning for moyamoya disease.

Management of large submacular hemorrhage in a patient undergoing neurosurgical intervention for moyamoya

Cindy S. Zhao, MD, MBA, Lucie Guo, MD, PhD, Akira Féliz, MS, Anna Toth, MD, PhD, Vinit B. Mahajan, MD, PhD, Charles M. T. DeBoer, MD, PhD

PDF Video 1

OCT angiography (cross-sectional view of right eye) obtained at initial presentation showing vessel tortuosity with high flow with no flow voids.

A 46-year-old woman with bilateral white retinal vessels

Joanne Christine E. Macenas-Wong, BSc (Pscyh), MD, DPBO, Aaron W. Joe, MD, PhD, FRCSC

PDF

Profuse bleeding from the left eye on presentation.

A 43-year-old woman with nontraumatic profuse ocular hemorrhage

Mohammad O. Tallouzi, BSc, MSc, PhD, PGCHE, Maryam Noeman, BSc, Matthew Azzopardi, MD, FRCOphth, Yu Jeat Chong, FRCOphth

PDF

The image shows a solitary translucent, brown-pigmented vitreous cyst observed in the anterior vitreous cavity in a 73-year-old man who was asymptomatic on presentation for routine examination.

Vitreous cyst in a 73-year-old man

Leandro Inferrera, MD, PhD, Andrea Gaggino, MD, Daniele Tognetto, MD

PDF

The monochrome and green digital filters enhance visualization during capsulorhexis, hydro-dissection, and cortex and viscoelastic removal. In addition, the high magnification and monochrome digital filter improve visualization of the endothelial layer, making it easier to detect the guttae.

Digitally assisted phaco-DMEK surgery

Luca Scartozzi, MD, Luigi Mosca, MD, Laura Guccione, MD, Romina Fasciani, MD, PhD, Stanislao Rizzo, MD

PDF Video

Still image of briskly positive Seidel test.

Seidel-positive corneal laceration

Melissa Yuan, MD

PDF

Optical coherence tomography revealed a submacular hemorrhage with an accompanying pigment epithelial detachment.

Massive submacular hemorrhage in pseudoxanthoma elasticum

Stéphane Abramowicz, MD, Adélaïde Toutée, MD, Rafik Belazzougui, MD, Bahram Bodaghi, MD, PhD

PDF

Dilated fundus examination revealed the presence of an extensive myelinated nerve fiber layer in the right eye surrounding the entire optic nerve, with feathery extensions superiorly.

Straatsma syndrome: unilateral myelinated retinal nerve fibre layer, high myopia, and amblyopia

Francisco Saulo Sampaio Cardoso Tavares, MD, Pâmmela Dayana Lopes Carrilho Machado, MD, Gabriel de Deus Vieira, MD

PDF

Slit-lamp examination revealed hyperemia and a wormlike, blood-filled conjunctival lymphatic vessel in the superotemporal bulbar conjunctiva.

Spontaneous resolution of conjunctival hemorrhagic lymphangiectasia

Kosuke Nagaoka, MD, Shinji Makino, MD, PhD

PDF

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