Bilateral anterior lens capsule ruptures in Alport syndrome: case series and literature review

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, Healed central capsular defect with opacification of capsular edges and underlying lens cortex.
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Published: Aug 4, 2024
DOI: https://doi.org/10.5693/djo.02.2024.03.001
Keywords:
Alport syndrome anterior lenticonus lens capsule rupture ocular features

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Danielle Gouws, MBChB
Department of Ophthalmology, Robert Mangaliso Sobukwe Hospital, Kimberley, South Africa
Dian P. van der Westhuizen, MBChB
Division of Ophthalmology, Tygerberg Academic Hospital and Stellenbosch University, Cape Town, South Africa
Kelsey V. Stuart, MBBCh, MSc, MRCSEd
NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom
https://orcid.org/0000-0001-7353-8774

Abstract

We present 3 cases of bilateral anterior lens capsule rupture, all leading to a subsequent diagnosis of Alport syndrome. Clinicians should be alert to the ocular and systemic features of Alport syndrome, especially when presented with a spontaneous rupture of the anterior lens capsule in young males. Ophthalmologists are often the first contact for patients with Alport syndrome, and a sound knowledge of the associated features will enable timely referral to other members of a multidisciplinary team required to treat such patients. Diagnosis and subsequent testing of affected families further aids in genetic counseling and early, comprehensive treatment.

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How to Cite
1.
Gouws D, van der Westhuizen DP, Stuart KV. Bilateral anterior lens capsule ruptures in Alport syndrome: case series and literature review. Digit J Ophthalmol. 2024;30(3). doi:10.5693/djo.02.2024.03.001
Issue
Vol. 30 No. 3 (2024)
Section
Case Reports
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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