Lethal mycotic pseudoaneurysm presenting as isolated sixth nerve palsy

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Rasna Bhanuman, MBBS, DNB
Shriram Varadharajan, DM
Karthik Kumar, DO
Virna M. Shah, DO

Abstract

Pseudoaneurysm of the internal carotid artery caused by skull base osteomyelitis (SBO) is a lethal condition seen in immunocompromised patients, predominantly those with diabetes mellitus. Cranial nerve involvement is a common complication and generally indicates a poor prognosis. We report the case of a 62-year-old diabetic patient who presented with isolated sixth cranial nerve palsy. She had uncontrolled blood sugar levels and high erythrocyte sedimentation rate, and she suffered from pyelonephritis.  Neuroimaging detected SBO with multiple secondary mycotic pseudoaneurysms prominent at the petrocavernous junction. Ischemia is the most common etiology for an isolated abducens nerve palsy, but in certain cases neuroimaging is warranted to prevent life-threatening complications. This case highlights the importance and urgency of identifying and managing such conditions.


 

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How to Cite
1.
Bhanuman R, Varadharajan S, Kumar KK, Shah VM. Lethal mycotic pseudoaneurysm presenting as isolated sixth nerve palsy. Digit J Ophthalmol. 2024;30(1):19-21. doi:10.5693/djo.02.2023.11.002
Section
Case Reports

References

Clark MPA, Pretorius PM, Byren I, Milford CA. Central or atypical skull base osteomyelitis: diagnosis and treatment. Skull Base 2009;19:247-54. DOI: https://doi.org/10.1055/s-0028-1115325

Mascitelli JR, De Leacy RA, Oermann EK, et al. Cervical-petrous internal carotid artery pseudoaneurysm presenting with otorrhagia treated with endovascular techniques. BMJ Case Rep 2014;2014:bcr2014011286. DOI: https://doi.org/10.1136/bcr-2014-011286

Budhiraja S, Sagar P, Kumar R, Sharma SC. Mycotic pseudoaneurysm of internal carotid artery induced by skull base osteomyelitis. Otol Neurotol 2019;40:e816-9. DOI: https://doi.org/10.1097/MAO.0000000000002343

Haider AS, Esianor BI, Shail MS, et al. Mycotic pseudoaneurysm associated with skull base osteomyelitis treated with endovascular embolization. Cureus 2017;9:e1622. DOI: https://doi.org/10.7759/cureus.1622

Lee WK, Mossop PJ, Little AF, et al. Infected (mycotic) aneurysms: spectrum of imaging appearances and management. Radiographics 2008;28:1853-68. DOI: https://doi.org/10.1148/rg.287085054

Khan MA, Quadri SAQ, Kazmi AS, et al. A comprehensive review of skull base osteomyelitis: diagnostic and therapeutic challenges among various presentations. Asian J Neurosurg 2018;13:959-70. DOI: https://doi.org/10.4103/ajns.AJNS_90_17

Singh A, Al Khabori M, Hyder MJ. Skull base osteomyelitis: diagnostic and therapeutic challenges in atypical presentation. Otolaryngol Head Neck Surg 2005;133:121-5. DOI: https://doi.org/10.1016/j.otohns.2005.03.024

Álvarez Jáñez F, Barriga LQ, Iñigo TR, Roldán Lora F. Diagnosis of skull base osteomyelitis. Radiographics 2021;41:156-74. DOI: https://doi.org/10.1148/rg.2021200046