Surgical outcome and pathological findings in macular epiretinal membrane caused by neurofibromatosis type 2

Hiroshi Kunikata, MD, PhD; Koji M. Nishiguchi, MD, PhD; Mika Watanabe, MD, PhD; Toru Nakazawa, MD, PhD

doi:10.5693/djo.02.2021.06.001

PDF XML

Published: Jan 21, 2022

DOI: https://doi.org/10.5693/djo.02.2021.06.001

Hiroshi Kunikata, MD, PhD

Department of Ophthalmology, Tohoku University Graduate School of Medicine, Miyagi, Japan; Department of Retinal Disease Control, Tohoku University Graduate School of Medicine, Miyagi, Japan

Koji M. Nishiguchi, MD, PhD

Department of Pathology, Tohoku University Graduate School of Medicine, Miyagi, Japan

Mika Watanabe, MD, PhD

Department of Pathology, Tohoku University Graduate School of Medicine, Miyagi, Japan

Toru Nakazawa, MD, PhD

Department of Ophthalmology, Tohoku University Graduate School of Medicine, Miyagi, Japan; Department of Retinal Disease Control, Tohoku University Graduate School of Medicine, Miyagi, Japan; Department of Advanced Ophthalmic Medicine, Tohoku University Graduate School of Medicine, Miyagi, Japan; Department of Ophthalmic Imaging and Information Analytics, Tohoku University Graduate School of Medicine, Miyagi, Japan

Abstract

We present surgical outcomes in a 10-year-old Japanese girl with neurofibromatosis type 2 (NF2)–induced epiretinal membrane (ERM). Her right eye underwent lens-sparing 27-gauge microincision vitrectomy surgery (MIVS) with ERM peeling. Decimal best-corrected visual acuity increased from 0.3 to 0.4 postoperatively. However, abnormal thickening of the macula persisted for 3 years. Staining of the extracted ERM revealed many cells positive for glial fibrillary acidic protein and nestin. Although removal of NF2-induced ERM with MIVS can improve visual acuity, the potential surgical risks require careful consideration on a case-by-case basis.

Downloads

Download data is not yet available.

How to Cite

Kunikata, MD, PhD H, Nishiguchi, MD, PhD KM, Watanabe, MD, PhD M, Nakazawa, MD, PhD T. Surgical outcome and pathological findings in macular epiretinal membrane caused by neurofibromatosis type 2. Digit J Ophthalmol. 2022;28(1):12-16. doi:10.5693/djo.02.2021.06.001

Issue

Vol. 28 No. 1 (2022)

Section

Case Reports

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

About us

Citation Indices

1.2

2022CiteScore

32nd percentile

Information

Make a Submission

Featured Content

Video-based surgical curriculum for open-globe injury repair, I: open-globe injury

As one of the most severe forms of ocular trauma, open-globe injury (OGI) causes significant vision loss. Timely and meticulous repair of these injuries can improve patient outcomes. This video-based educational curriculum is intended to serve as a quick and efficient yet comprehensive reference for OGI repair. We hope that these video-based articles help surgeons and trainees from around the world find answers to specific surgical questions in OGI management. The curriculum has been divided into six separate review articles, each authored by a different set of authors, to facilitate a systematic and practical approach to the subject of wound types and repair techniques. The first article highlights pertinent terminology and standardized definitions for OGI trauma, which aids in communication, prognostication, and outcomes research.

Article Sidebar

Main Article Content

Abstract

Downloads

Article Details