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A 57-year-old man with leukocytosis and sphenoid sinus disease
Digital Journal of Ophthalmology 2020
Volume 26, Number 2
April 24, 2020
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Ansuya P. Deosaran, MD | Department of Ophthalmology, Louisiana State University, New Orleans, Louisiana
Ahmaida Zeglam, MD | Department of Ophthalmology, University of Florida, Gainesville, Florida
Mary K. Wilson, BS | College of Medicine, University of Florida, Gainesville, Florida
Andres Gonzalez, MD | Department of Ophthalmology, University of Florida, Gainesville, Florida
Matthew J. Gray, MD | Department of Ophthalmology, University of Florida, Gainesville, Florida
Differential Diagnosis
The differential diagnosis for invasive fungal sinusitis includes an infection with Aspergillus, Rhizopus, Mucorales, Fusarium, and dematiaceous fungi.(1,2). These fungi cause tissue necrosis, vascular thrombosis, and infarction (2). Among these, the most likely fungi are Aspergillus and Rhizopus species.(2) Identification of the organism is made with culture, immunohistochemistry, and in situ hybridization.(2,3)
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