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A 45-year-old man with spontaneous hyphema of the right eye
Digital Journal of Ophthalmology 2017
Volume 23, Number 3
August 9, 2017
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Jay C. Wang, MD | Department of Ophthalmology, Massachusetts Eye and Ear, Boston, Massachusetts
Maggie B. Hymowitz, MD | Department of Ophthalmology, Massachusetts Eye and Ear, Boston, Massachusetts
Differential Diagnosis
The differential diagnosis for spontaneous hyphema in the setting of a unilateral anterior uveitis includes infectious and inflammatory causes. Viral infections, such as herpes simplex and herpes zoster, must also be considered, because these can present with a keratouveitis and, rarely, hyphema. Inflammatory causes include Fuchs heterochromic iridocyclitis, HLA-B27-associated uveitis, lens-induced uveitis, juvenile xanthogranulomatosis, and juvenile idiopathic arthritis in young patients. In patients who are pseudophakic, uveitis-glaucoma-hyphema syndrome is also part of the differential diagnosis.
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